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The GUDMAP database--an online resource for genitourinary research.

TitleThe GUDMAP database--an online resource for genitourinary research.
Publication TypeJournal Article
Year of Publication2011
AuthorsHarding, SD, Armit, C, Armstrong, J, Brennan, J, Cheng, Y, Haggarty, B, Houghton, D, Lloyd-MacGilp, S, Pi, X, Roochun, Y, Sharghi, M, Tindal, C, McMahon, AP, Gottesman, B, Little, MH, Georgas, K, Aronow, BJ, S Potter, S, Brunskill, EW, E Southard-Smith, M, Mendelsohn, C, Baldock, RA, Davies, JA, Davidson, D
JournalDevelopment
Volume138
Issue13
Pagination2845-53
Date Published2011 Jul
ISSN1477-9129
KeywordsAnimals, Databases, Genetic, Humans, Internet, Mice, Software, Urogenital System
Abstract

The GenitoUrinary Development Molecular Anatomy Project (GUDMAP) is an international consortium working to generate gene expression data and transgenic mice. GUDMAP includes data from large-scale in situ hybridisation screens (wholemount and section) and microarray gene expression data of microdissected, laser-captured and FACS-sorted components of the developing mouse genitourinary (GU) system. These expression data are annotated using a high-resolution anatomy ontology specific to the developing murine GU system. GUDMAP data are freely accessible at www.gudmap.org via easy-to-use interfaces. This curated, high-resolution dataset serves as a powerful resource for biologists, clinicians and bioinformaticians interested in the developing urogenital system. This paper gives examples of how the data have been used to address problems in developmental biology and provides a primer for those wishing to use the database in their own research.

DOI10.1242/dev.063594
Alternate JournalDevelopment
PubMed ID21652655
PubMed Central IDPMC3188593
Grant ListDK070136 / DK / NIDDK NIH HHS / United States
DK070181 / DK / NIDDK NIH HHS / United States
DK070200 / DK / NIDDK NIH HHS / United States
R01 DK061459-01A1 / DK / NIDDK NIH HHS / United States
R01 DK061459-01A1S1 / DK / NIDDK NIH HHS / United States
R01 DK061459-02 / DK / NIDDK NIH HHS / United States
R01 DK061459-03 / DK / NIDDK NIH HHS / United States
R01 DK061459-04 / DK / NIDDK NIH HHS / United States
R01 DK061459-05 / DK / NIDDK NIH HHS / United States
R01 DK061459-06 / DK / NIDDK NIH HHS / United States
R01 DK061459-07 / DK / NIDDK NIH HHS / United States
R01 DK061459-07S1 / DK / NIDDK NIH HHS / United States
R01 DK061459-08 / DK / NIDDK NIH HHS / United States
R01 DK061459-09 / DK / NIDDK NIH HHS / United States
R56 DK082963-01 / DK / NIDDK NIH HHS / United States

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